Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection.

نویسندگان

  • Anthony Cacciapuoti
  • Judith Halpern
  • Cara Mendrick
  • Christine Norris
  • Reena Patel
  • David Loebenberg
چکیده

The interaction of posaconazole and caspofungin was evaluated in concomitant treatment of Aspergillus fumigatus (two strains) or A. flavus (one strain) systemic infections in immunocompetent mice. Survival curves for mice treated with the combinations were compared statistically with those for mice treated with the component monotherapies. No antagonism was observed.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 50 7  شماره 

صفحات  -

تاریخ انتشار 2006